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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
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Updated: Jun 3, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Potentially lethal suicide attempts using sharp objects during psychotic illness.

Olav B Nielssen1, Matthew M Large

  • 1Clinical Research Unit for Anxiety and Depression, School of Psychiatry, University of New South Wales at St. Vincent's Hospital, Darlinghurst, Sydney, Australia.

Crisis
|March 5, 2011
PubMed
Summary
This summary is machine-generated.

Psychosis is linked to dangerous suicide attempts with sharp objects. Patients experiencing their first episode of psychosis, especially those untreated with antipsychotic medication, face the highest risk.

Related Experiment Videos

Last Updated: Jun 3, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Forensic Psychiatry

Background:

  • Serious violence toward self and others is more prevalent during the initial phase of psychosis compared to post-treatment periods.
  • Understanding risk factors in the first episode of psychosis is crucial for early intervention.

Purpose of the Study:

  • To determine the prevalence of psychotic illness among individuals who survived life-threatening suicide attempts involving sharp objects.
  • To assess the proportion of these patients who had not received prior antipsychotic medication treatment for psychosis.

Main Methods:

  • A retrospective audit of medical records was conducted for patients who survived self-inflicted stab wounds or neck lacerations.
  • The study included survivors treated at three major teaching hospitals in Sydney, Australia.

Main Results:

  • The study examined 95 survivors of self-inflicted cutting or stabbing wounds.
  • A diagnosis of psychotic illness was identified in 48% of cases (46 out of 95).
  • Of those with psychosis, 57% (26 cases) had never received antipsychotic treatment, indicating a first episode of psychosis.

Conclusions:

  • A significant association exists between psychosis and lethal suicide attempts utilizing sharp instruments.
  • Individuals with untreated first-episode psychosis represent a particularly vulnerable group requiring targeted interventions.