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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

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Human Blastocyst Biopsy and Vitrification
10:59

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Published on: July 26, 2019

Embryo selection in IVF.

Sebastiaan Mastenbroek1, Fulco van der Veen, Abbas Aflatoonian

  • 1Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. s.mastenbroek@amc.uva.nl

Human Reproduction (Oxford, England)
|March 5, 2011
PubMed
Summary
This summary is machine-generated.

Embryo selection in in vitro fertilization (IVF) may not improve live birth rates, as all embryos can now be cryopreserved and transferred. This challenges traditional IVF success optimization strategies.

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Area of Science:

  • Reproductive Medicine
  • Embryology
  • In Vitro Fertilization (IVF)

Background:

  • Historically, embryo selection was crucial for optimizing in vitro fertilization (IVF) success rates.
  • Cryopreserved embryos were believed to have lower implantation potential post-thaw.

Purpose of the Study:

  • To evaluate the impact of modern cryopreservation techniques on embryo viability and pregnancy rates.
  • To reassess the necessity and efficacy of embryo selection methods in current IVF protocols.

Main Methods:

  • Review of accumulating evidence on cryopreservation and subsequent embryo transfer outcomes.
  • Analysis of pregnancy rates comparing selective versus non-selective embryo transfer strategies.

Main Results:

  • Recent data suggest that all embryos can be cryopreserved without compromising, and potentially improving, pregnancy rates.
  • When all embryos are transferred sequentially, live birth rates per stimulated IVF cycle cannot be improved by selection.

Conclusions:

  • Embryo selection may not enhance live birth rates in IVF cycles utilizing modern cryopreservation.
  • The primary benefit of embryo selection might be reducing the time to pregnancy by prioritizing embryos with higher implantation potential.