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Updated: Jun 3, 2026

Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
Published on: September 23, 2021
ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins
Kamil Tamiola1, Frans A A Mulder
1Department of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands. k.tamiola@rug.nl
Unlabelled:
We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts.
Availability:
The ncIDP-assign extension is available at http://www.protein-nmr.org/.
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