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Related Concept Videos

Applications Of NMR In Biology01:25

Applications Of NMR In Biology

3.3K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
3.3K
Nuclear Magnetic Resonance (NMR): Overview01:07

Nuclear Magnetic Resonance (NMR): Overview

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Nuclear magnetic resonance (NMR) is a phenomenon exhibited by certain nuclei that can absorb characteristic radio frequency radiation under certain conditions. NMR has been extensively applied in molecular spectroscopy and medical diagnostic imaging. In both these applications, the molecule or subject under study is placed in a magnetic field and irradiated with radio frequency energy.
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
6.8K
NMR Spectrometers: Overview01:20

NMR Spectrometers: Overview

2.0K
NMR spectrometers consist of a strong magnet, a radiofrequency transmitter, and a detector attached to a computer console for recording spectra of samples containing NMR-active nuclei. In first-generation NMR instruments called continuous-wave spectrometers, the resonance frequencies of the nuclei are determined by frequency-sweep or field-sweep methods. The magnetic field strength is fixed and the rf signal is swept in the former, while the radiofrequency signal is fixed and the magnetic field...
2.0K
Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

870
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
870
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

1.2K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
1.2K
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

993
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
993

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Updated: May 3, 2026

Integration of 5G Experimentation Infrastructures into a Multi-Site NFV Ecosystem
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Moving NMR infrastructures to remote access capabilities.

James Tolchard1, Tanguy Le Marchand1, Ruud L E G Aspers2

  • 1Ecole Normale Supérieure de Lyon, CNRS, Lyon 1 Université, Centre de RMN à Hauts Champs de Lyon (CRMN), 5 rue de la Doua, 69100 Villeurbanne, France.

Progress in Nuclear Magnetic Resonance Spectroscopy
|May 1, 2026
PubMed
Summary
This summary is machine-generated.

Remote access to Nuclear Magnetic Resonance (NMR) instruments is now feasible, offering enhanced accessibility and sustainability. This shift requires standardized protocols and collaborative efforts for global, equitable data acquisition.

Keywords:
Data management and securityNMR infrastructureRemote accessStandard operating procedures (SOPs)SustainabilityWorkflow design

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Area of Science:

  • Analytical Chemistry
  • Biophysics
  • Materials Science

Background:

  • Historically, Nuclear Magnetic Resonance (NMR) research required in-person access to specialized facilities.
  • The COVID-19 pandemic accelerated the exploration and validation of remote access technologies for NMR.

Purpose of the Study:

  • To review the challenges and opportunities of remote access for NMR instrumentation.
  • To propose a unified framework for enhancing NMR facility accessibility and sustainability.

Main Methods:

  • Literature review of remote access technologies and their application to NMR.
  • Analysis of key components: sample handling, authentication, instrument control, and data management.
  • Examination of requirements for a unified remote access framework.

Main Results:

  • Remote NMR access is technically feasible and offers strategic advantages.
  • Key challenges include standardizing sample handling, ensuring secure access, and managing data.
  • Opportunities lie in improving sustainability and global accessibility of NMR resources.

Conclusions:

  • A collaborative approach is essential to develop best practices for remote NMR.
  • Standardized protocols are crucial for reproducibility and high-quality data acquisition.
  • Implementing remote access can lead to more equitable global access to NMR infrastructure.