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Updated: Jun 3, 2026
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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
Expression of HSV Proteins in Bacteria
1Neurovirology Research Laboratories, Institute of Neurological Sciences, Southern General Hospital, University of Glasgow, Scotland, UK.
Methods in Molecular Medicine
|March 5, 2011
Summary
Bacterial expression systems enable large-scale production of herpes simplex virus (HSV) proteins. These viral proteins are valuable for analysis and creating antibodies.
Area of Science:
- Molecular Biology
- Virology
- Biochemistry
Background:
- Herpes simplex virus (HSV) protein expression is crucial for research.
- Bacterial expression systems offer a method for producing viral proteins.
Purpose of the Study:
- To describe the utility of bacterial expression systems for generating HSV polypeptides.
- To highlight the applications of these produced proteins in research.
Main Methods:
- Utilizing bacterial expression systems to produce HSV polypeptides.
- Expressing proteins in full-length native form or as fusion proteins.
Main Results:
- Successful generation of large quantities of specific HSV proteins.
- Production of proteins suitable for biochemical and functional analysis.
- Generation of immunogens for antisera production.
Conclusions:
- Bacterial expression systems are effective for producing HSV proteins.
- These proteins are valuable tools for virology research and antibody development.
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