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Quantifying Human Monocyte Chemotaxis In Vitro and Murine Lymphocyte Trafficking In Vivo
Published on: October 30, 2017
Chemotaxis of in vitro cultured human dendritic cells
W Luini1, G D'Amico, S Bernasconi
1Department of Immunology and Cell Biology, "Mario Negri" Institute, Milan, Italy.
Methods in Molecular Medicine
|March 5, 2011
Abstract:
Chemotaxis is defined as the directional locomotion of cells sensing a gradient of the stimulus. Some cell types, such as monocytes and neutrophils, can be considered as "professional migrants" and for many years the study of chemotaxis has been applied to these cells. However, other cell types including fibroblasts, melanoma cells, keratinocytes, and vascular endothelial cells exhibit directional locomotion in vitro.
