Mitogenic effects of lectins on epithelial cells
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Updated: Jun 3, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
Published on: August 27, 2013
1Gastroenterology Research Group, Department of Medicine, University of Liverpool, UK.
Abstract:
The specific binding of lectins to the carbohydrate moieties of glycoproteins and glycohpids on the cell surface has been shown to result in a variety of signal transduction processes (1,2). One of the most dramatic effects of the interaction of lectins with cells is mitogenic stimulation, e.g., the triggering of nondividing lymphocytes into a state of growth and proliferation (3) which has led to the extensive and successful use of lectins in the analysis of events occuring during lymphocyte activation and proliferation (4,5).
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