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The ribosome and TORC2: collaborators for cell growth

Xiaoduo Xie1, Kun-Liang Guan

  • 1Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093-0815, USA.

Cell
|March 8, 2011
PubMed
Summary

The target of rapamycin complex 2 (TORC2), a cell growth regulator, is activated by direct ribosome association. This mechanism may link TORC2 activity to the cell's growth capacity.

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