Cri-du-chat syndrome: dental considerations and report of case

Cri-du-chat syndrome is a severe disease resulting from a deletion of the short arm of chromosome number 5. The basic medical disorder includes dysmorphic facies, mental retardation, and a striking catlike cry in infancy. Because of significant oral anomalies and difficulty in behavior management, the syndrome is of particular interest to the dental practitioner. A case with many of the typical medical findings and significant dental considerations is reported. An aggressive preventive dentistry program is essential. A thorough understanding of the medical and developmental problems of the patient with cri-du-chat syndrome ensures safe and effective dental care.