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Updated: Jun 3, 2026

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
11:44

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

Controlling site selectivity in Pd-catalyzed oxidative cross-coupling reactions.

Thomas W Lyons1, Kami L Hull, Melanie S Sanford

  • 1Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|March 9, 2011
PubMed
Summary

This study reveals how quinone promoters and carboxylate ligands control site selectivity in palladium-catalyzed oxidative coupling reactions. Ligand substitution can reverse selectivity, offering new synthetic control for arene functionalization.

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