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Related Experiment Video

Updated: Jun 3, 2026

Differentiation, Maintenance, and Analysis of Human Retinal Pigment Epithelium Cells: A Disease-in-a-dish Model for BEST1 Mutations

Differentiation, Maintenance, and Analysis of Human Retinal Pigment Epithelium Cells: A Disease-in-a-dish Model for BEST1 Mutations

Published on: August 24, 2018

Dyschromatosis universalis hereditaria: a case report.

Carounanidy Udayashankar¹, Amiya Kumar Nath

¹Indira Gandhi Medical College and Research Institute, Puducherry, India.

Dermatology Online Journal

|March 9, 2011

Summary

Dyschromatosis universalis hereditaria (DUH) is a rare genetic skin disorder. This report details a unique Indian case with extensive skin, nail, hair, and oral mucous membrane involvement, highlighting its varied presentation.

Area of Science:

Dermatology
Medical Genetics

Background:

Dyschromatosis universalis hereditaria (DUH) is an autosomal dominant disorder.
Characterized by widespread hypo- and hyperpigmented macules.

Observation:

A case report of an Indian patient with DUH.
The patient presented with extensive skin involvement affecting the face, palms, and soles.
Oral mucous membranes, including the tongue, were also affected.

Findings:

The patient exhibited nail changes.
Scalp hair involvement and keratosis pilaris were noted.
This presentation suggests a broader spectrum of DUH manifestations.

Implications:

Highlights the diverse clinical spectrum of Dyschromatosis universalis hereditaria.

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Emphasizes the importance of thorough dermatological examination in suspected DUH cases.

Contributes to understanding DUH in diverse ethnic populations.