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Updated: Jun 3, 2026

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Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection
Published on: November 17, 2023
Modification of Ag nanoparticles with mixed thiols for improved SERS detection of poorly adsorbing target molecules:
Alan Stewart1, Steven E J Bell
1Queen's University Belfast, Belfast BT9 5AG, UK.
Abstract:
Here we report an example of a mixed thiol monolayer on the surface of Ag nanoparticles which promotes adsorption and quantitative SERS detection of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"); the thiols in the mixed monolayers act synergistically since MDMA does not adsorb onto colloids modified with either of the thiols separately.

