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Mapping between the OBO and OWL ontology languages.
Syed Hamid Tirmizi1, Stuart Aitken, Dilvan A Moreira
1Department of Computer Science, The University of Texas at Austin, Austin, Texas 78701, USA. hamid@cs.utexas.edu.
Journal of Biomedical Semantics
|March 11, 2011
Summary
We developed a method to convert Open Biomedical Ontologies (OBO) to the Web Ontology Language (OWL), enabling broader use of biomedical data. This lossless transformation ensures no knowledge is lost, bridging the gap between ontology languages.
Area of Science:
- Biomedical informatics
- Semantic Web technologies
- Ontology engineering
Background:
- Biomedical ontologies organize complex biological and medical concepts.
- NCBO BioPortal hosts numerous ontologies, primarily in Open Biomedical Ontology (OBO) and Web Ontology Language (OWL) formats.
- Leveraging OWL's Semantic Web features for OBO content requires effective transformation methods.
Purpose of the Study:
- To develop a methodology for translating OBO ontologies into OWL.
- To create a standard, common mapping between OBO and OWL constructs.
- To enable language-independent use of biomedical ontology content.
Main Methods:
- Developed a methodology guided by Semantic Web organization principles.
- Decomposed OBO constructs into those with direct OWL equivalents and those requiring deeper analysis.
- Defined transformations for all OBO constructs to ensure comprehensive mapping.
- Implemented the mapping to produce OWL-DL, a computationally efficient subset of OWL.
Main Results:
- A methodology for translating OBO to OWL was successfully developed.
- Most OBO constructs were mapped to direct OWL equivalents, with specific transformations for the remainder.
- The mapping produces OWL-DL, ensuring computational efficiency and correctness.
- A Java implementation of the mapping is integrated into the Gene Ontology project.
Conclusions:
- The transformation system provides a lossless roundtrip mapping for OBO to OWL.
- This facilitates the integration and use of biomedical ontology data across different systems.
- The work establishes a roadmap for bridging OBO and OWL, promoting interoperability.
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