Related Experiment Video
Updated: Jun 3, 2026
11:41
Mapping Mammalian 3D Genome Interactions with Micro-C-XL
Published on: November 3, 2023
Status of the cattle genome map
1Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, UK. del2@aber.ac.uk
Cytogenetic and Genome Research
|March 11, 2011
Summary
Cattle genome mapping has advanced significantly, identifying thousands of genes and disease markers. Future research will focus on breed-specific genetic differences for improved cattle breeding and diagnostics.
Area of Science:
- * Genomics and Bioinformatics
- * Animal Genetics and Breeding
Background:
- * The cattle genome map has expanded dramatically over 30 years, from 4 genes to over 22,000 identified genes.
- * This progress is driven by the agricultural and scientific importance of cattle genomics.
- * Mapping efforts have revealed major quantitative trait loci (QTL) and disease genes.
Purpose of the Study:
- * To review the advancements in cattle genome mapping and its implications.
- * To highlight the discovery of genetic factors influencing traits and diseases in cattle.
- * To discuss the future directions in cattle genome analysis.
Main Methods:
- * Review of linkage and physical mapping projects.
- * Analysis of cattle genome sequence assembly.
- * Comparative genomics with other mammalian species.
Main Results:
- * Identification of over 22,000 genes in the cattle genome.
- * Discovery of quantitative trait nucleotides (QTNs) and disease-associated genes.
- * Unveiling unique features of the cattle genome through interspecies comparison.
Conclusions:
- * Cattle genome research has provided valuable insights into traits and diseases.
- * Advancements facilitate marker-assisted selection and disease diagnostics.
- * Future research will leverage cost-effective sequencing for breed-specific genetic analysis.
More Related Videos
Related Concept Videos
00:58Genomic DNA in Eukaryotes
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
03:36Genome Annotation and Assembly
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
01:11Genome-wide Association Studies-GWAS
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
02:02Genomics
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...