Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cirrhosis I: Introduction

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...

Atypical Pneumonia

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

From Childhood to Adulthood: A Case of Congenital Tracheal Stenosis.

Cureus·2025

Same author

Primary Pulmonary Epithelial-Myoepithelial Carcinoma: A Case Report and Comprehensive Literature Review of a Rare Lung Neoplasm.

Cureus·2025

Same author

The use of water in wineries: A review.

The Science of the total environment·2024

Same author

Energy efficiency in winemaking industry: Challenges and opportunities.

The Science of the total environment·2024

Same author

Water consumption assessment and classification in industrial buildings - The case study of Continental Advanced Antenna, Vila Real, Portugal.

The Science of the total environment·2023

Same author

Factors associated with diet quality among Brazilian individuals with cardiovascular diseases.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2023

Search research articles

Related Experiment Videos

Castleman's disease: an unusual presentation.

Nicole Murinello¹, Cristina Matos, Fernando Nogueira

¹Department of Pulmonology, Egas Moniz Hospital, Western Lisbon Hospital Center, Lisbon, Portugal. nicole_murinello@iol.pt

Jornal Brasileiro De Pneumologia : Publicacao Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia

|March 11, 2011

Summary

Castleman's disease, a rare lymphoproliferative disorder, can manifest as a solitary pulmonary nodule. This case highlights its importance in the differential diagnosis of lung nodules.

Related Experiment Videos

Area of Science:

Pulmonology
Oncology
Pathology

Background:

Castleman's disease is a rare lymphoproliferative disorder.
It typically involves lymph nodes but rarely affects lung parenchyma.

Observation:

A case of Castleman's disease presenting as a solitary pulmonary nodule in an asymptomatic immunocompetent male is reported.
This represents an extremely rare histological variant and presentation.

Findings:

The patient underwent a successful lobectomy with favorable postoperative recovery.
Only five previous reports of Castleman's disease presenting as a solitary pulmonary nodule have been documented in the last decade.

Implications:

Castleman's disease should be considered in the differential diagnosis of pulmonary nodules.
This rare presentation emphasizes the need for broad diagnostic considerations in pulmonary pathology.