Primary Pulmonary Epithelial-Myoepithelial Carcinoma: A Case Report and Comprehensive Literature Review of a Rare...

Primary epithelial-myoepithelial carcinoma (EMC) of the lung is a rare subtype of pulmonary tumors. Originating from bronchial submucosal glands, EMC shares histopathological characteristics with its salivary gland counterparts and typically presents as a low-grade malignancy. Due to its rarity, there is limited literature to guide diagnosis and management. We report the case of a 75-year-old male with a history of smoking and chronic conditions who presented with persistent right-sided back pain. Imaging revealed a para-hilar lesion in the right lung, later confirmed as EMC through bronchoscopy and histopathological analysis. Staging studies excluded local invasion and metastasis, and a multidisciplinary team recommended surgical resection. The patient underwent surgery without complications, and histological analysis of the resected specimen confirmed the diagnosis. At follow-up in the pulmonary oncology clinic, no recurrence or metastasis was observed. This case highlights the importance of a multidisciplinary approach for diagnosing and managing rare pulmonary neoplasms. Bronchoscopy and histopathological analysis played a crucial role in achieving an accurate diagnosis. This case contributes to the limited data on EMC and supports surgical intervention as the primary treatment option for localized disease.