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Related Experiment Video

Updated: Jun 3, 2026

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
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A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors

Published on: October 30, 2016

Vaccinia virus as an expression vector.

A Talavera1, J M Rodriguez

  • 1Centro Nacional de Biotechnologia, Madrid, Spain.

Methods in Molecular Biology (Clifton, N.J.)
|March 11, 2011
PubMed
Summary
This summary is machine-generated.

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Vaccinia virus (Vv) belongs to the Poxviridae family, with most genera infecting vertebrates. Notably, leporipoxviruses like Fibroma and Myxoma are the only tumorigenic viruses within this family, causing tumors in rabbits.

Area of Science:

  • Virology
  • Infectious Diseases
  • Oncology

Background:

  • Poxviridae is a diverse viral family with seven genera.
  • Most poxviruses infect vertebrates, but Entomopoxvirus infects insects.
  • Leporipoxvirus genus includes Fibroma and Myxoma viruses, known for causing tumors in rabbits.

Purpose of the Study:

  • To provide an overview of the Poxviridae family.
  • To highlight the host range of different poxvirus genera.
  • To identify tumorigenic viruses within the Poxviridae family.

Main Methods:

  • Literature review of Poxviridae classification and characteristics.
  • Analysis of host-pathogen interactions for different genera.
  • Identification of unique viral properties, such as tumorigenicity.

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Methodology for the Efficient Generation of Fluorescently Tagged Vaccinia Virus Proteins
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Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
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Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

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Last Updated: Jun 3, 2026

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
09:16

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors

Published on: October 30, 2016

Methodology for the Efficient Generation of Fluorescently Tagged Vaccinia Virus Proteins
09:27

Methodology for the Efficient Generation of Fluorescently Tagged Vaccinia Virus Proteins

Published on: January 17, 2014

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Main Results:

  • Vaccinia virus (Vv) is classified under the Orthopoxvirus genus within Poxviridae.
  • Seven genera exist in Poxviridae, with most targeting vertebrates.
  • Fibroma and Myxoma viruses are the sole tumorigenic members, affecting rabbits.

Conclusions:

  • The Poxviridae family exhibits diverse host specificities.
  • Leporipoxviruses represent a unique group due to their tumorigenic potential.
  • Understanding poxvirus diversity is crucial for disease management and research.