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Published on: April 21, 2019
Comparison of serum specific IgE and skin prick test in polysensitized children
Giorgio Ciprandi1, Mara De Amici, Gianluigi Marseglia
1Department of Ilnternal Medicine, Azienda Ospedaliera Universitaria San Martino - University of Geno, Genoa, Italy. gio.cip@libero.it
Background:
Skin prick test (SPT) and serum specific IgE (ssIgE) measurements are the most common methods used to diagnose allergy. The aim of this study was to evaluate serum specific-IgE in a large group of polysensitized patients with the same SPT result (such as ++++) comparing the two diagnostic methods.
Methods:
Four hundred ninety-four children (310 males; median age 10 years) suffering from allergic rhinitis were studied. Serum specific-IgE values were measured by ImmunoCap assay. Skin prick test was also performed.
Results:
There was a significant difference (p < 0.0001) among serum specific-IgE values in these polysensitized patients.
Conclusions:
The ss-IgE measurements in polysensitized patients seem to be more appropriate than SPT.
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