Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Tuberculosis

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dual sequential testing for latent tuberculosis infection in BCG-vaccinated contacts: is it worth it?

Thorax·2025

Same author

Country-wide genotyping of Mycobacterium tuberculosis complex in Singapore, 2011-2017.

Tuberculosis (Edinburgh, Scotland)·2022

Same author

Joint Associations of Multiple Lifestyle Factors With Risk of Active Tuberculosis in the Population: The Singapore Chinese Health Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2021

Same author

Recurrent Tuberculosis Disease in Singapore.

Open forum infectious diseases·2021

Same author

Correction: Perspectives of Singaporean biomedical researchers and research support staff on actual and ideal IRB review functions and characteristics: A quantitative analysis.

PloS one·2021

Same author

Modulation effects of Dendrobium officinale on gut microbiota of type 2 diabetes model mice.

FEMS microbiology letters·2021

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Tuberculosis among foreign-born persons, Singapore, 2000-2009.

Khin Mar Kyi Win¹, Cynthia B E Chee, Liang Shen

¹Tuberculosis Control Unit, Tan Tock Seng Hospital, Singapore. kyi_win_khin_mar@ttsh.com.sg

Emerging Infectious Diseases

|March 12, 2011

Summary

The proportion of foreign-born individuals with tuberculosis (TB) in Singapore rose significantly between 2004 and 2009. This increase was largely driven by unskilled workers migrating from high-TB incidence countries.

Related Experiment Videos

Last Updated: Jun 3, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Area of Science:

Public Health
Epidemiology
Infectious Diseases

Background:

Tuberculosis (TB) remains a global health concern.
Understanding the demographics of TB cases is crucial for effective control strategies.
Singapore has a significant foreign-born population, necessitating an examination of TB trends within this group.

Purpose of the Study:

To determine the proportion of foreign-born individuals diagnosed with tuberculosis (TB) in Singapore.
To analyze trends in foreign-born TB cases over a defined period.
To identify demographic factors associated with an increase in foreign-born TB patients.

Main Methods:

Retrospective analysis of national TB registry data.
Calculation of the proportion of TB cases among foreign-born individuals.
Stratification of cases by country of origin and occupational status.

Main Results:

The proportion of foreign-born persons with TB in Singapore increased from 25.5% in 2004 to 37.6% in 2009.
Unskilled workers constituted the largest group among foreign-born TB case-patients.
This demographic also showed the greatest increase in TB incidence during the study period.

Conclusions:

The rising proportion of TB among foreign-born individuals in Singapore is a significant public health finding.
Targeted interventions for migrant worker populations, particularly unskilled laborers from high-incidence regions, are warranted.
Enhanced surveillance and prevention strategies are needed to curb the spread of TB in this vulnerable group.