Related Experiment Video
Updated: Jun 3, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
[Hypobaric interval hypoxia as a tool for improving tolerance of harmful occupational factors]
Abstract:
The method of hypobaric interval hypoxia (HIH) has been developed and approved for application in aerospace, military, prophylactic and rehabilitative medicine. A course of H1H included 10 one-hour daily sessions of hypobaria and interval hypoxia simulating ascent to an altitude from 3 to 5 km a.s.l. Each session comprised a 7 minute exposure to hypoxia (breathing rarified air) alternating with a 3 minute exposure to hyperoxia (breathing oxygen) without a change of the altitude simulated in the low-pressure chamber. The first session included ascent to 3 km, in each of the following sessions (from 2nd to 4th) the altitude was successively increased by 500 m and reached 5 km in sessions 5-10. HIH was shown to be highly efficacious in improving the functional state of the organism and its resistance to unfavourable environmental conditions; also it can be used to correct changes of these parameters.
Related Concept Videos
Hypoxia
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Hyperpnea and Hyperventilation
Oxygen Transport in the Blood
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...

