Periorbital lesions
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Updated: Jun 3, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1Department of Metabolic and Medical Sciences, Section of Dermatology, University of Genoa, Viale Benedetto XV, 7, 16122 Genova, Italy. rebdermo@unige.it
Abstract:
Periorbital lesions are dermatologic manifestations affecting the area around the eyes, excluding the eyelids. They can be classified according to their nature and morphology. Although types of skin disorders affect the periorbital area, only those with a prevalent or prominent location will be mentioned, and clinical descriptions will be confined to the rarer entities. Inflammatory lesions include erythematous and erythematous scaling, eczematous and urticarial lesions, vesicular and bullous lesions, and granulomatous lesions. Purpuras, infections, and infestations may be present as well. Benign and malignant tumors are common. Metabolic disorders include some rare entities, such as mucinosis and amyloidosis, but also commoner manifestations such as xanthelasma. Histiocytosis is rare but does occur in prevalent locations. Hair and pigmentary disorders are common, and aging-related damage is most visible in the periorbital area.