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Published on: May 31, 2024
Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors
Nils Griebenow1, Timo Flessner, Anja Buchmueller
1Bayer Pharma AG, Global Drug Discovery, Medicinal Chemistry Wuppertal, Building 460, D-42096 Wuppertal, Germany. nils.griebenow@bayer.com
Bioorganic & Medicinal Chemistry Letters
|March 15, 2011
Abstract:
Novel squalene synthase inhibitors are disclosed. SAR and pharmacological profile of selected compounds are discussed.
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