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Related Experiment Video

Updated: Jun 3, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Published on: February 6, 2021

Post-traumatic Infectious Endophthalmitis.

Neelakshi Bhagat1, Saya Nagori, Marco Zarbin

  • 1The Institute of Ophthalmology and Visual Science, New Jersey Medical School, Newark, New Jersey, USA. bhagatne@umdnj.edu

Survey of Ophthalmology
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

Post-traumatic endophthalmitis, an eye infection after open globe injury, is a serious complication. Prompt antibiotic treatment is crucial for preserving vision, with various prophylactic regimens considered for penetrating trauma.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Post-traumatic endophthalmitis is a rare but severe complication following open globe injuries.
  • Key risk factors include intraocular foreign bodies, lens rupture, delayed repair, and contaminated trauma.

Purpose of the Study:

  • To summarize risk factors, visual prognosis determinants, and treatment strategies for post-traumatic endophthalmitis.
  • To discuss antibiotic prophylaxis in penetrating ocular trauma.

Main Methods:

  • Literature review and synthesis of current knowledge on post-traumatic endophthalmitis.
  • Analysis of factors influencing visual outcomes and treatment efficacy.

Main Results:

  • Visual prognosis is influenced by microbial virulence, retinal status, treatment timing, foreign body presence, and injury severity.
  • Emergent systemic and intravitreal antibiotics are recommended for treatment.

Conclusions:

  • Antibiotic prophylaxis should be considered for penetrating ocular trauma.
  • Optimal prophylactic regimens (oral, IV followed by oral, or intravitreal plus oral antibiotics) require further determination.