Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Corneal donor material selection.

Z N Zakov, C H Dohlman, H D Perry

    American Journal of Ophthalmology
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Finding an Optimal Corneal Xenograft Using Comparative Analysis of Corneal Matrix Proteins Across Species.

    Scientific reports·2019
    Same author

    Cost effectiveness of the type II Boston keratoprosthesis.

    Eye (London, England)·2010
    Same author

    Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitis.

    Current eye research·2003
    Same author

    Histopathology of explanted collar button keratoprostheses: a clinicopathologic correlation.

    Cornea·2003
    Same author

    Keratoprosthesis: an update.

    Current opinion in ophthalmology·2001
    Same author

    Amniotic membrane inlay and overlay grafting for corneal epithelial defects and stromal ulcers.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2001
    Same journal

    Corneal sensitivity changes and nerve plexus abnormalities in noninfectious anterior uveitis.

    American journal of ophthalmology·2026
    Same journal

    Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

    American journal of ophthalmology·2026
    Same journal

    Forging Ahead: The Need for Improved Representation in Academic Ophthalmology.

    American journal of ophthalmology·2026
    Same journal

    Clinical Utility of Ultra-Widefield Swept-Source OCT for Intraocular Tumors: Comparison With Ultrasonography, SD-OCT, and MRI.

    American journal of ophthalmology·2026
    Same journal

    Therapeutic Advances in Corneal Scar management: Topical Treatments, Mesenchymal Cell Therapy and Stromal Transplantation.

    American journal of ophthalmology·2026
    Same journal

    Increased Risk for Ocular Surface Neoplasia in Recipients of Solid Organ Transplant.

    American journal of ophthalmology·2026
    See all related articles

    Donor eyes require careful screening for corneal transplantation. Histologic examination revealed leukemia, fungal infections, and metastatic cancer, highlighting risks associated with certain donor conditions.

    Area of Science:

    • Ophthalmology
    • Transplant Surgery
    • Pathology

    Background:

    • Donor eye suitability is critical for successful corneal transplantation.
    • Histologic examination of donor eyes can reveal unexpected pathologies.
    • Identifying contraindications for donation prevents disease transmission.

    Purpose of the Study:

    • To report histologic findings in donor eyes.
    • To identify potential risks and contraindications for corneal donation.
    • To emphasize the importance of rigorous donor screening.

    Main Methods:

    • Histologic examination of donor eyes.
    • Review of medical histories and causes of death.
    • Pathological analysis of ocular tissues.

    Related Experiment Videos

    Main Results:

    • Identified massive leukemic infiltration in one donor eye.
    • Found fungal microabscesses (Cryptococcus neoformans) in another donor eye.
    • Detected metastatic anaplastic cells in the choroid of a third donor eye.

    Conclusions:

    • Donor eyes are unacceptable if death resulted from chronic neurologic disorders (unless trauma-related), sepsis, hepatitis, jaundice, active viral infections, syphilis, or positive serology.
    • Extreme caution is advised for donors with ocular/systemic malignancy, long-term diseases (especially with immunosuppression), prior eye disease, or previous intraocular surgery.