Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 3, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Partial breast irradiation by brachytherapy, 1927.

Jesse N Aronowitz1

  • 1Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, MA 01605, USA. jesse.aronowitz@umassmemorial.org

Brachytherapy
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In Regard to Likhacheva et al.

International journal of radiation oncology, biology, physics·2017
Same author

In Regard to Foray.

International journal of radiation oncology, biology, physics·2017
Same author

Transformative Technologies: The Crookes, Coolidge, and Cascade Tubes.

International journal of radiation oncology, biology, physics·2016
Same author

Early Use of Adjuvant Breast Radiation Therapy and the Recognition of Radiation Pneumonitis.

International journal of radiation oncology, biology, physics·2016
Same author

The Other Radiation Therapy.

International journal of radiation oncology, biology, physics·2015
Same author

Afterloading: The Technique That Rescued Brachytherapy.

International journal of radiation oncology, biology, physics·2015
Same journal

Addressing barriers to care: A proposed model to predict prolonged treatment time among patients with locally advanced cervical cancer.

Brachytherapy·2026
Same journal

EM-tracked MR-US live fusion and needle location in gynecologic brachytherapy.

Brachytherapy·2026
Same journal

Contour and dosimetric evaluation of an in-room mobile CBCT scanner for cylinder based brachytherapy.

Brachytherapy·2026
Same journal

Brachytherapy for rectal cancer: An overview of clinical competency development in contemporary practice.

Brachytherapy·2026
Same journal

Deep learning-based automatic segmentation of rectal tumors in endoscopic images.

Brachytherapy·2026
Same journal

Online educational program for CT-based image-guided adaptive brachytherapy in cervical cancer: The BrachyAcademy experience.

Brachytherapy·2026
See all related articles

Geoffrey Keynes showed that brachytherapy, a form of radiotherapy, was as effective as mastectomy for breast cancer treatment. This conservative approach preserved body form and function, offering a preferable alternative.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Background:

  • Radical mastectomy was the standard treatment for breast cancer during the mid-20th century.
  • Geoffrey Keynes pioneered conservative treatment strategies for breast cancer management.

Observation:

  • Keynes investigated the efficacy of brachytherapy as an alternative to radical mastectomy.
  • His work focused on breast cancer management, aiming to improve patient outcomes and quality of life.

Findings:

  • Brachytherapy, with or without local excision, demonstrated equal effectiveness to radical mastectomy in treating breast cancer.
  • Keynes's technique preserved the patient's body form and function, unlike more invasive procedures.

Implications:

More Related Videos

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Related Experiment Videos

Last Updated: Jun 3, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

  • Established conservative surgery combined with radiotherapy as a preferred breast cancer treatment option.
  • Influenced the evolution of breast cancer management towards less invasive and more function-sparing techniques.
  • Highlighted the importance of patient form and function in surgical decision-making for breast cancer.