Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is formed in...
Ion Exchange01:17

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or basic...
Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microliter-Scale Stereolithography Enables High-Resolution 3D Printing of Functional Extraction Sorbents.

Analytical chemistry·2026
Same author

QTL mapping and key candidate gene identification of resistance to frogeye leaf spot (<i>Cercospora sojina</i>) in soybean.

Frontiers in plant science·2026
Same author

Surface modification and ligand loading effects in imidazolium-based zwitterionic stationary phases for hydrophilic interaction chromatography.

Journal of chromatography. A·2026
Same author

A biocompatible and recyclable ionic liquid platform for long-term and high temperature plant RNA stabilization.

Analytica chimica acta·2026
Same author

Fluorinated ionic liquids as gas chromatographic stationary phases for the separation of volatile per- and polyfluoroalkyl substances.

Analytica chimica acta·2026
Same author

Fluorinated Polymeric Ionic Liquids Enable Selective Preconcentration of Volatile Perfluoroalkyl Substances.

Analytical chemistry·2026
Same journal

Whole-body mass spectrometry imaging reveals metabolome and lipid peroxidation heterogeneity in zebrafish xenografts of esophageal squamous cell carcinoma.

Analytical and bioanalytical chemistry·2026
Same journal

A robust and validated method for the determination of 21 urinary metabolites of 15 plasticizers, including phthalates, DEHTP, and DINCH, by online SPE and liquid chromatography-tandem mass spectrometry.

Analytical and bioanalytical chemistry·2026
Same journal

A label-free membrane-based biosensor array with AuNP-modified PDMS for sensitive and specific detection of alpha-fetoprotein.

Analytical and bioanalytical chemistry·2026
Same journal

Smartphone-integrated one-step colorimetric glucose detection at physiological pH enabled by a haloperoxidase mimic.

Analytical and bioanalytical chemistry·2026
Same journal

Chemiluminescence functionalized magnetic nanoparticles-based biosensor for sensitive detection of glucose, uric acid, and cholesterol.

Analytical and bioanalytical chemistry·2026
Same journal

Single-cell mass spectrometry imaging: platform advances for multimodal spatial omics.

Analytical and bioanalytical chemistry·2026
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
10:42

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids

Published on: August 10, 2016

Task-specific microextractions using ionic liquids.

Qichao Zhao1, Jared L Anderson

  • 1Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street; MS 602, Toledo, OH 43606, USA.

Analytical and Bioanalytical Chemistry
|March 15, 2011
PubMed
Summary
This summary is machine-generated.

Ionic liquids (ILs) offer advantages over traditional solvents for analytical microextractions. Their tunable properties enhance extraction selectivity, efficiency, and sensitivity in techniques like single drop, solid-phase, and dispersive liquid-liquid microextraction.

More Related Videos

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature
11:04

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature

Published on: December 20, 2016

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
09:44

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery

Published on: September 26, 2025

Related Experiment Videos

Last Updated: Jun 3, 2026

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
10:42

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids

Published on: August 10, 2016

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature
11:04

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature

Published on: December 20, 2016

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
09:44

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery

Published on: September 26, 2025

Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Ionic liquids (ILs) are versatile solvents with tunable physical and chemical properties.
  • Traditional organic solvents pose environmental and safety concerns in analytical chemistry.
  • Microextraction techniques require efficient and selective extraction media.

Purpose of the Study:

  • To provide an overview of ionic liquids in analytical microextraction.
  • To highlight trends in using ILs for task-specific extractions.
  • To discuss the advantages of ILs over conventional solvents.

Main Methods:

  • Review of scientific literature on ionic liquids and microextraction.
  • Focus on single drop microextraction (SDME).
  • Focus on solid-phase microextraction (SPME).
  • Focus on dispersive liquid-liquid microextraction (DLLME).

Main Results:

  • Ionic liquids offer enhanced selectivity, efficiency, and sensitivity in microextraction.
  • Tunable properties of ILs allow for task-specific extraction method development.
  • ILs present a greener alternative to traditional organic solvents.

Conclusions:

  • Ionic liquids are highly promising for advanced analytical microextraction techniques.
  • Tailoring IL structure enables optimized analyte extraction.
  • Further research into IL-based microextractions is warranted for various applications.