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Structural studies of proteins in solution using proton nuclear magnetic resonance

D Neuhaus1, P A Evans

  • 1MRC Laboratory of Molecular Biology, Addenbrookes Hospital Site, Cambridge, UK.

Methods in Molecular Biology (Clifton, N.J.)
|March 15, 2011
PubMed
Summary

Nuclear magnetic resonance (NMR) spectroscopy, particularly two-dimensional (2D) NMR, enables detailed three-dimensional protein structure determination in solution. This technique allows for precise assignment of signals and analysis of nuclear connectivities for structural insights.

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