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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
[Changes in the fatty-acid spectrum of epidermal structures in various age group patients with psoriasis]
Abstract:
The paper depicts changes in the epidermal fatty-acid spectrum in patients with psoriasis progressing to the stage of dermatosis in various age groups (18-40 and 41-60 years). The parameters studied in healthy individuals showed age-related differences in the pool of saturated and unsaturated fatty acids (SCFA). Heterodirectional changes in the epidermal levels of saturated, polyenic, and monoenic fatty acids were recorded in the lesion foci and visually healthy skin of patients with psoriasis depending on age.
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