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Four new polyoxygenated gorgosterols from the gorgonian Isis hippuris
Mohammad Helal Uddin1, Novriyandi Hanif, Agus Trianto
1Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.
Abstract:
Four new polyoxygenated steroids (1-4) together with four known ones (5-8) have been isolated from the gorgonian Isis hippuris. The structures of the new compounds have been elucidated by spectroscopic analysis and chemical conversion. All of the new steroids showed moderate cytotoxicity against cultured NBT-T2 cells.
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Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
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