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Updated: Jun 3, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

Improving perinatal Group B streptococcus screening with process indicators.

Marion Albouy-Llaty1, Cédric Nadeau, Emmanuelle Descombes

  • 1Medical Evaluation Unit, Pharmacy-Public Health Pole, Poitiers University Hospital, University of Poitiers, Poitiers, France. marion.albouy-llaty@chu-poitiers.fr

Journal of Evaluation in Clinical Practice
|March 19, 2011
PubMed
Summary
This summary is machine-generated.

Group B Streptococcus (GBS) screening in pregnant women increased significantly after mandatory data collection. However, neonatal GBS infections persist, indicating a need to re-evaluate screening test performance.

Related Experiment Videos

Last Updated: Jun 3, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Infectious Disease Prevention

Background:

  • Group B Streptococcus (GBS) neonatal infection is preventable through antenatal screening.
  • French guidelines since 2001 recommend GBS screening between 34-38 weeks gestation.
  • Assessing adherence to GBS screening guidelines among healthcare providers was crucial.

Purpose of the Study:

  • To evaluate adherence to GBS screening guidelines in pregnant women.
  • To assess the impact of mandatory data collection on GBS screening practices.
  • To analyze outcomes related to GBS screening and intrapartum antibiotic prophylaxis.

Main Methods:

  • Utilized a mandatory obstetric database merged with bacteriological and pediatric data (2006-2008).
  • Defined process indicators for pregnant women delivering from 37 weeks gestation and neonates hospitalized for GBS infection.
  • Analyzed screening rates, timing, intrapartum antibiotic prophylaxis (IAP) administration, and neonatal outcomes.

Main Results:

  • GBS colonization prevalence ranged from 13-18% over the study period.
  • GBS screening rates increased significantly (86% to 90%), with correct-term screening rising from 89% to 96%.
  • Intrapartum antibiotic prophylaxis (IAP) administration decreased significantly (84% to 70%), while correct IAP remained stable at 75%.

Conclusions:

  • Mandatory data collection improved GBS screening adherence and correct-term screening rates.
  • Despite improved screening, neonatal GBS infections continue to occur.
  • Re-evaluation of GBS screening test performance is necessary to further reduce neonatal infections.