Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteomics01:33

Proteomics

9.7K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.7K
Tumor Progression02:07

Tumor Progression

7.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
Hybridoma Technology01:31

Hybridoma Technology

17.6K
Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
17.6K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

4.8K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.8K
Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

3.4K
Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
3.4K
Photoluminescence: Applications01:14

Photoluminescence: Applications

1.1K
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Analysis of mRNA Alternative Splicing in the Trigeminal Ganglion at Different Stages of Trigeminal Neuropathic Pain in Mice.

Journal of pain research·2026
Same author

The impact of immune microenvironment on local control of ductal carcinoma in situ receiving breast conservative therapy.

Breast cancer research : BCR·2026
Same author

LAMTOR5 promotes hepatoma growth in mice by disrupting LC3-p62-mediated autophagy and preventing p62 proteasome degradation.

Acta pharmacologica Sinica·2026
Same author

Hepatic and Renal Toxicity of Gardenia Yellow: Repeated-Dose Assessment and Human Oral Equivalent Dose Prediction via IVIVE.

Journal of agricultural and food chemistry·2025
Same author

Photoelectrocatalytic XAT strategy for the generation of alkyl radicals to synthesize alkylated 3-CF<sub>3</sub>-2-oxindoles.

Chemical communications (Cambridge, England)·2025
Same author

Comprehensive analysis of mode of action for cadmium-induced renal tubular dysfunction: a case study integrating high-throughput sequencing, targeted cellular assays, and human data.

Environment international·2025
Same journal

[Mechanical regulation mechanism on vascular remodeling induced by hypertension].

Sheng li ke xue jin zhan [Progress in physiology]·2018
Same journal

[Progress on research methods of transcription factors].

Sheng li ke xue jin zhan [Progress in physiology]·2018
Same journal

[Regulatory effect of miR-21 on peripheral nerve injury and regulation function].

Sheng li ke xue jin zhan [Progress in physiology]·2018
Same journal

[The protective effects and mechanisms of PPARγ in ischemia-reperfusion injury of tissues].

Sheng li ke xue jin zhan [Progress in physiology]·2018
Same journal

[Nitric Oxide Signaling Pathway and Vascular Activity].

Sheng li ke xue jin zhan [Progress in physiology]·2018
Same journal

[The Regulation Effects of Carbon Monoxide in Cardiovascular Systems].

Sheng li ke xue jin zhan [Progress in physiology]·2018
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
07:28

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics

Published on: October 19, 2021

3.6K

[Proteomic technology: its progress and application in microcirculation research].

Fei-Fei Xu1, Xiu-Hua Liu

  • 1Department of Pathophysiology, Chinese PLA General Hospital, Beijing 100853, China.

Sheng Li Ke Xue Jin Zhan [Progress in Physiology]
|March 23, 2011
PubMed
Summary
This summary is machine-generated.

Proteomics offers new insights into microcirculation, a vital bodily system. This review explores how proteomics technology advances our understanding of microcirculation

More Related Videos

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
10:40

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model

Published on: August 4, 2012

13.1K
The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation
07:19

The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation

Published on: June 10, 2011

33.0K

Related Experiment Videos

Last Updated: Jan 30, 2026

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
07:28

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics

Published on: October 19, 2021

3.6K
Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
10:40

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model

Published on: August 4, 2012

13.1K
The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation
07:19

The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation

Published on: June 10, 2011

33.0K

Area of Science:

  • Physiology and Molecular Biology
  • Proteomics and Systems Biology

Context:

  • Microcirculation is essential for physiological functions and implicated in numerous diseases.
  • Understanding microcirculation's complex molecular dynamics is crucial for disease pathogenesis and treatment.

Purpose:

  • To review the advancements in proteomics technology.
  • To highlight the application of proteomics in studying microcirculation under physiological and pathological conditions.

Summary:

  • Microcirculation plays a direct role in material, energy, and information transfer throughout the body.
  • Changes in microcirculation are linked to various diseases, including cardiovascular, metabolic, and inflammatory conditions.
  • Proteomics provides a comprehensive approach to analyze protein expression and interactions, elucidating molecular mechanisms of microcirculation.

Impact:

  • Proteomics enables a deeper understanding of the molecular basis of microcirculation dysfunction.
  • This knowledge can pave the way for novel diagnostic and therapeutic strategies for microcirculation-related diseases.