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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
Published on: July 16, 2013
[The role of extracellular ATP in the airway]
Hong-Mei Guo1, Yu-Li Luo, Wen-Liang Zhou
1School of Life Science, SUN Yat-sen University, Guangzhou 510275, China.
Abstract:
ATP serves not only as an energy source for all cell types but as an extracellular messenger for autocrine and paracrine signaling involving in a versatile role in modulating various cellular functions. This review summarizes the efflux pathways of ATP released from airway epithelial cells, the signal pathways through which ATP induces ion transport by the epithelia of airway, as well as its epithelium-dependent modulation of smooth muscle contraction of airway and the mechanism underlying in airway diseases.
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