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Updated: Jun 3, 2026

Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform
Published on: May 10, 2024
[Progress in the study of UDP-glucuronosyltransferase gene polymorphism]
Dong Guo1, Liang-Fang Pang, Hong-Hao Zhou
1Institute of Clinical Pharmacology, Xiang-Ya Medical College, Central South University, Changsha 410078, China.
Abstract:
Uridinediphosphoglucuronate-glucuronosyltransferase (UGT) is the most important enzyme of the body in phase II metabolism. UGT is widely distributed in multiple tissues, including liver, kidney and intestine, which metabolizes a large number of exogenous toxic substances and endogenous substances. Studies found that UGT1 A genetic polymorphism is one of the important reasons for the variability of glucuronic acid metabolism between individuals. This paper reviews the current concept and new advances on UGT gene mutation.
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