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Related Concept Videos

Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
Sampling Methods: Sample Types01:18

Sampling Methods: Sample Types

Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...

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Related Experiment Video

Updated: Jun 3, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

[Cannabis and urine samples].

Andreas Austgulen Westin1

  • 1Avdeling for klinisk farmakologi, St. Olavs hospital, 7006 Trondheim, Norway. andreas.westin@legemidler.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|March 23, 2011
PubMed
Summary

Cannabinoids like THCCOOH can be detected in urine for up to three months after cannabis cessation. Differentiating new use from residual excretion requires quantitative analysis and consideration of usage extent.

Area of Science:

  • Forensic toxicology
  • Pharmacokinetics
  • Analytical chemistry

Context:

  • Cannabis use and detection remain significant public health and legal concerns.
  • Understanding cannabinoid excretion is crucial for accurate drug testing.
  • Urine drug screening is a common method for detecting cannabis use.

Purpose:

  • To review the detection duration of cannabinoids in urine post-cessation.
  • To clarify the interpretation of urinary cannabinoid test results.
  • To differentiate between new cannabis intake and residual excretion.

Summary:

  • Cannabis use is typically identified by detecting 11-nor-9-carboxy-Delta9-tetrahydrocannabinol (THCCOOH) in urine.
  • Urinary THCCOOH detection can persist for several days to three months after cessation, varying with usage extent.

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  • Accurate interpretation necessitates quantitative measurement of THCCOOH, considering urine dilution and collection timing.

    • Impact:

    • Provides guidance for clinicians and laboratories in interpreting cannabis drug test results.
    • Highlights the challenges in distinguishing recent cannabis use from chronic use in forensic toxicology.
    • Emphasizes the importance of a collaborative approach involving client, clinician, and laboratory for precise interpretation.