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Related Concept Videos

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Theoretical Approaches to Psychological Disorder01:29

Theoretical Approaches to Psychological Disorder

The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Structuralism01:26

Structuralism

Structuralism, an early psychological theory developed by Wilhelm Wundt and his student Edward Bradford Titchener, sought to dissect the human mind into its most fundamental components. Wundt's groundbreaking work in his laboratory set the stage for Titchener to define structuralism's goal as cataloging the "atoms" of the mind—sensations, images, and feelings—akin to how chemists identify elements of matter.
Titchener's approach to structuralism was unique. He employed introspection, a method...

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Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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[Deconstructing schizophrenia. Dimensional models or division into subtypes?].

M Jäger1, K Frasch, F U Lang

  • 1Klinik für Psychiatrie und Psychotherapie II, Universität Ulm, Bezirkskrankenhaus Günzburg, Ludwig-Heilmeyer-Str. 2, 89312, Günzburg, Deutschland. Markus.Jaeger@bkh-guenzburg.de

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Summary
This summary is machine-generated.

Future diagnostic models for schizophrenia are being debated, questioning current concepts due to a lack of neurobiological validation. Historical psychopathological foundations suggest dimensional or subtype approaches may offer new diagnostic frameworks.

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Last Updated: Jun 3, 2026

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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Published on: March 8, 2018

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Area of Science:

  • Psychiatry and Mental Health
  • Neuroscience
  • Clinical Psychology

Context:

  • Current diagnostic criteria for schizophrenia, including ICD-11 and DSM-V, are under review.
  • Previous attempts at neurobiological and familial validation of schizophrenia concepts have yielded insufficient results.
  • The limitations of current diagnostic paradigms necessitate exploration of alternative approaches.

Purpose:

  • To analyze the historical psychopathological roots influencing current debates on schizophrenia diagnosis.
  • To evaluate proposed dimensional diagnostic models and subtype classifications for schizophrenia.
  • To explore the potential of a triaxial diagnostic system for integrating different conceptualizations of schizophrenia.

Summary:

  • The discussion around diagnosing schizophrenic psychoses is evolving, challenging existing concepts due to inadequate validation.
  • Historical analysis reveals Kurt Schneider's first-rank symptoms as a foundation for current nominalistic views, contrasting with Klaus Conrad and Karl Leonhard's contributions to dimensional and subtype models.
  • A proposed triaxial diagnostic system, incorporating syndromes, course types, and etiology, could reconcile these divergent approaches to schizophrenia diagnosis.

Impact:

  • This review provides a historical perspective on the conceptualization of schizophrenia, informing future diagnostic revisions.
  • It highlights the need for a more nuanced diagnostic framework beyond current categorical approaches.
  • The proposed triaxial system offers a potential pathway for a more comprehensive and integrated understanding of schizophrenic disorders.