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Updated: Jun 3, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Heart failure resulting from giant left atrial synovial sarcoma metastasis
B Winkler1, M Grapow, M Seeberger
1Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland. bwinkler@uhbs.ch
Abstract:
Synovial sarcoma metastasis affecting the heart and infiltrating the mitral valve is a very rare pathology. We report the case of a 44-year-old male treated with chemotherapy for atypical synovial sarcoma of the oral mucosa who presented to our clinic after cardiac decompensation with a presumptive diagnosis of myxoma of the left atrium. A large necrotic tumour positive for CK 22, EMA, CD 99 and BCL-2 but negative for translocation in COBRA-FISH analysis by break-apart probe could be excised and revealed a very rare subtype of synovial sarcoma metastasis arising from the endocard of the left atrium. The tumour was resected and the mitral valve reconstructed through ring annuloplasty.
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