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Related Experiment Video

Updated: Jun 3, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

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Published on: February 2, 2024

Two new triterpenoids from Zygophyllum eurypterum.

Shazia Iqbal¹, Afsar Khan, Viqar Uddin Ahmad

¹H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.

Natural Product Communications

|March 24, 2011

Summary

Two novel triterpenoids, atriplicoide A and B, were identified in Zygophyllum eurypterum. Their structures were elucidated using advanced spectroscopic techniques, expanding the known chemical diversity of this plant genus.

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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

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Published on: October 4, 2019

Area of Science:

Natural Product Chemistry
Phytochemistry
Organic Chemistry

Background:

Zygophyllum eurypterum is a plant species known for its potential medicinal properties.
Triterpenoids are a diverse class of natural products with a wide range of biological activities.
Isolation and structural elucidation of new compounds contribute to understanding plant chemical diversity.

Purpose of the Study:

To isolate and characterize novel triterpenoids from Zygophyllum eurypterum.
To determine the chemical structures of the isolated compounds using spectroscopic methods.

Main Methods:

Extraction of the whole plant of Zygophyllum eurypterum using n-butanol.
Purification of compounds from the extract.
Structure elucidation using various spectroscopic techniques: EI-MS, IR, 1H-NMR, 13C-NMR, and 2D-NMR (HMQC, HMBC, COSY, NOESY).

Main Results:

Two new triterpenoids, named atriplicoide A and atriplicoide B, were successfully isolated.
The structure of atriplicoide A was determined as 30-carboxy-3beta,24-dihydroxy-urs-28,13beta-lactam-N-acetate.
The structure of atriplicoide B was determined as 3beta,24-dihydroxyursan-28,13beta-olide.

Conclusions:

The study successfully identified and characterized two new triterpenoids from Zygophyllum eurypterum.
The findings contribute to the phytochemical knowledge of the Zygophyllum genus.
The detailed structural information provides a basis for further investigation into the biological activities of these compounds.