Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.

Heterogeneous Catalysis

Heterogeneous Catalysis

Heterogeneous catalysis involves a catalyst in a different phase from the reactants. It is a process where the catalyst and the reactants are in distinct phases, typically solid and gas or liquid.Most heterogeneous catalysts are metals, metal oxides, or acids. The list includes transition metals like iron (Fe), cobalt (Co), nickel (Ni), palladium (Pd), platinum (Pt), chromium (Cr), manganese (Mn), tungsten (W), silver (Ag), and copper (Cu). These metals possess partially vacant d orbitals that...

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.

Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Breath-based detection of oral diseases using sensors and machine learning.

Journal of dentistry·2026

Same author

Encapsulation of Exosomal Volatile Organic Compounds for Modulating the NF-κB Pathway in Monocytes.

ACS bio & med chem Au·2026

Same author

A multi-modal approach for correlative evaluation of osteogenesis and osteoclastogenesis on laser-treated titanium, TiAl6V4, and stainless steel.

Biomaterials advances·2026

Same author

Stiff to Soft: A Protein-Based Buffer Layer for Improving the Long-Term Performance of Microneedle Sensors.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Calcium Phosphate Mineralization of Bulk Alginate Hydrogels Composites With Metal and Metal Oxide Nanoparticles.

Macromolecular bioscience·2026

Same author

Saturated Salt Hydrogel Engineering for Tunable ZnO Ultraviolet Sensor Performance and Mitigated Humidity Interference.

ACS applied materials & interfaces·2026

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Soft Lithographic Functionalization and Patterning Oxide-free Silicon and Germanium

Soft Lithographic Functionalization and Patterning Oxide-free Silicon and Germanium

Published on: December 16, 2011

Catalyst-free functionalization for versatile modification of nonoxidized silicon structures.

Sreenivasa Reddy Puniredd¹, Ossama Assad, Thomas Stelzner

¹The Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel.

Langmuir : the ACS Journal of Surfaces and Colloids

|March 24, 2011

Summary

This study introduces a simple, catalyst-free method for functionalizing silicon (Si) surfaces and nanowires. This versatile technique enables stable organic and inorganic material attachment for advanced electronic and sensing devices.

More Related Videos

Preparation of Functional Silica Using a Bioinspired Method

Preparation of Functional Silica Using a Bioinspired Method

Published on: August 1, 2018

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

Related Experiment Videos

Last Updated: Jun 3, 2026

Soft Lithographic Functionalization and Patterning Oxide-free Silicon and Germanium

Soft Lithographic Functionalization and Patterning Oxide-free Silicon and Germanium

Published on: December 16, 2011

Preparation of Functional Silica Using a Bioinspired Method

Preparation of Functional Silica Using a Bioinspired Method

Published on: August 1, 2018

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

Area of Science:

Materials Science
Surface Chemistry
Nanotechnology

Background:

Silicon (Si) nanowires and substrates are crucial for nanoelectronic and biosensing applications.
Surface functionalization is key to tailoring Si-based devices for specific applications.
Existing methods often involve catalysts, leading to residues and affecting sample stability.

Purpose of the Study:

To develop a simple, catalyst-free method for versatile functionalization of Si nanowires and Si(111) surfaces.
To enable the attachment of both organic and inorganic species.
To control cross-linker density without compromising Si sample stability.

Main Methods:

A novel, catalyst-free surface modification route was employed.
The method allows for controlled formation of monolayers with diverse termination groups.
Density of reactive cross-linkers can be precisely managed.

Main Results:

Achieved highly versatile subsequent functionalization on Si nanowires and Si(111) substrates.
Demonstrated successful immobilization of both organic and inorganic (nanomaterial) species.
Ensured no metallic or catalyst residues on the functionalized Si surfaces, preserving sample stability.

Conclusions:

The developed method offers a stable and residue-free approach for Si surface functionalization.
This technique opens avenues for creating advanced molecule-based optoelectronic and biosensing devices.
Immobilization of nanomaterials on Si enables applications in molecular switches, memory, and nanoelectronics.