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Honeycomb lung: history and current concepts
Hiroaki Arakawa1, Koichi Honma
1Department of Radiology, Dokkyo Medical University, 880 Kita-Kobayashi, Mibu, Tochigi 3210293, Japan. arakawa@dokkyomed.ac.jp
AJR. American Journal of Roentgenology
|March 24, 2011
Summary
Honeycomb lung, a sign of end-stage pulmonary fibrosis, has evolved in definition. Understanding its imaging is crucial for diagnosing usual interstitial pneumonia and differentiating it from other conditions.
Area of Science:
- Pulmonary Medicine
- Radiology
- Pathology
Background:
- Honeycomb lung historically described various cystic pathologies.
- Currently, it signifies end-stage pulmonary fibrosis on imaging.
- Distinguishing honeycomb lung from mimics is clinically important.
Purpose of the Study:
- To review the historical evolution of the term 'honeycomb lung'.
- To detail the characteristic imaging findings of honeycomb lung.
- To highlight its significance in diagnosing pulmonary fibrosis.
Main Methods:
- Literature review on the definition and history of honeycomb lung.
- Analysis of imaging features associated with honeycomb lung.
- Discussion of differential diagnoses that mimic honeycomb lung.
Main Results:
- The term 'honeycomb lung' has transitioned from a general descriptor to a specific indicator of advanced fibrosis.
- Characteristic cystic changes in a subpleural, peripheral, and posterior distribution are key imaging findings.
- Usual interstitial pneumonia frequently presents with honeycomb lung, but other conditions can mimic this appearance.
Conclusions:
- Honeycomb lung is a critical computed tomography (CT) finding in usual interstitial pneumonia.
- Radiologists must recognize that diverse pathologic processes can present as honeycomb lung.
- Accurate identification and understanding of honeycomb lung are essential for patient diagnosis and management.
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