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Updated: Jun 3, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Ankylosing spondylitis presented as unilateral optic neuritis in a young woman
Yen-Shou Chou1, Da-Wen Lu, Jian-Tong Chen
1Department of Ophthalmology, Tri-Service General Hospital, Taipei, Taiwan.
Purpose:
To report a case of ankylosing spondylitis that initially presented as unilateral optic neuritis.
Methods:
Case report.
Design:
Clinical findings and treatment are presented. A 31-year-old woman presented with unilateral optic neuritis in her right eye. Her symptom improved following pulse steroid therapy. Unfortunately, she developed severe pain and weakness in her bilateral knee and ankle joints during follow-up. Further investigation revealed a positive finding of HLA-B27 and bilateral sacroiliitis. Ankylosing spondylitis was confirmed and was treated with Salazine and Mobic.
Conclusions:
Optic neuritis is rarely the first symptom of AS. Careful surveying and prompt treatment is necessary.
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