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Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
Published on: November 30, 2022
Biospecimen reporting for improved study quality (BRISQ)
Helen M Moore1, Andrea B Kelly, Scott D Jewell
1Office of Biorepositories and Biospecimen Research, National Cancer Institute, Bethesda, Maryland, USA.
Cancer Cytopathology
|March 25, 2011
Summary
Standardizing human biospecimen handling information is crucial for reproducible research. The Biospecimen Reporting for Improved Study Quality (BRISQ) guidelines aim to improve data consistency and interpretation.
Area of Science:
- Biomedical research
- Clinical diagnostics
- Translational science
Background:
- Human biospecimens undergo preanalytical variations affecting molecular composition and experimental reproducibility.
- Inconsistent reporting of biospecimen handling details hinders accurate interpretation and comparison of research findings.
Framework:
- The Biospecimen Reporting for Improved Study Quality (BRISQ) provides standardized recommendations for reporting preanalytical variables.
- BRISQ guidelines are designed for universal application across studies utilizing human biospecimens.
Implementation:
- BRISQ aims to enhance the quality and consistency of information reported in scientific publications and regulatory submissions.
- Standardized reporting facilitates better evaluation, interpretation, and comparison of experimental results.
Implications:
- Improved biospecimen data quality strengthens research integrity and reproducibility.
- Adherence to BRISQ reassures patients and advocates that their contributions are valued and respected.
