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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Mild and selective vanadium-catalyzed oxidation of benzylic, allylic, and propargylic alcohols using air
Susan K Hanson1, Ruilian Wu, L A Pete Silks
1Chemistry and Biosciences Divisions, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA. skhanson@lanl.gov
Abstract:
Transition metal-catalyzed aerobic alcohol oxidation is an attractive method for the synthesis of carbonyl compounds, but most catalytic systems feature precious metals and require pure oxygen. The vanadium complex (HQ)(2)V(V)(O)(O(i)Pr) (2 mol %, HQ = 8-quinolinate) and NEt(3) (10 mol %) catalyze the oxidation of benzylic, allylic, and propargylic alcohols with air. The catalyst can be easily prepared under air using commercially available reagents and is effective for a wide range of primary and secondary alcohols.
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