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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...

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Updated: Jun 3, 2026

Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Viral asthma: implications for clinical practice.

Roger Menendez1, Michael D Goldman

  • 1Allergy and Asthma Center of El Paso, El Paso, TX, USA;

Journal of Asthma and Allergy
|March 26, 2011
PubMed
Summary
This summary is machine-generated.

Viral respiratory infections significantly impact asthma development and severity throughout life. Inefficient repair after viral injury in asthmatics drives disease patterns, prompting research into new antiviral therapies.

Keywords:
asthmaclinical trialsepidemiologyexacerbationsphenotypesrhinoviruses

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

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Last Updated: Jun 3, 2026

Methodology for Sputum Induction and Laboratory Processing
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Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Immunology

Background:

  • Asthma's natural history is closely linked to viral respiratory infections.
  • The cycle of viral injury and impaired healing contributes to asthma severity.
  • The specific host response in asthmatics to viral infections remains unclear.

Purpose of the Study:

  • To elucidate the role of viral infections in the pathogenesis of asthma.
  • To understand the mechanisms behind asthma exacerbations triggered by viruses.
  • To explore novel therapeutic targets for asthma prevention and treatment.

Main Methods:

  • Review of existing literature on asthma and viral respiratory infections.
  • Analysis of clinical patterns of asthma severity in relation to infection history.
  • Identification of key molecular and cellular pathways involved in host response.

Main Results:

  • Viral infections are a primary driver of asthma's natural history across all age groups.
  • Inefficient repair processes following viral-induced acute injury explain observed asthma severity.
  • Viruses contribute to both intermittent and persistent asthma, affecting atopic and nonatopic phenotypes.

Conclusions:

  • Targeting viral infections is crucial for managing asthma.
  • Future therapies should focus on primary prevention with antiviral vaccines and secondary prevention with antiviral agents or immunomodulators.
  • Boosting innate antiviral immunity and modulating inflammatory cascades are promising strategies.