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Isolation and Culture of Primary Mouse Keratinocytes from Neonatal and Adult Mouse Skin
Published on: July 14, 2017
Children and newborn skin care and prevention
Juliana Dumêt Fernandes1, Maria Cecília Rivitti Machado, Zilda Najjar Prado de Oliveira
1Department of Dermatology, Clinics Hospital, Faculty of Medicine, University of Sao Paulo, SP, Brazil. jdumet@gmail.com
Abstract:
Neonatal skin suffers a progressive adaptation to the extrauterine environment and special care is needed during this period. This skin is very sensitive, thin and fragile. Immaturity of the epidermal barrier reduces the defense against the excessive proliferation of microbes and makes the skin more vulnerable to trauma and percutaneous drug toxicity. Because of the peculiar characteristics of newborn, infant and children's skin, the use of cosmetic products designed for hygiene and protection requires caution. In order to preserve the integrity of neonatal and child's skin, this article reviewed basic preventive care practices in relation to hygiene, bathing, cleansing agents, topical products and their percutaneous toxicity.
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