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Updated: Jun 3, 2026

Optical Trapping of Nanoparticles

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Multifunctional microgel magnetic/optical traps for SERS ultradetection.

Rafael Contreras-Cáceres¹, Sara Abalde-Cela, Pablo Guardia-Girós

¹Departamento de Química Física, and Unidad Asociada CSIC-Universidade de Vigo, 36310, Vigo, Spain.

Langmuir : the ACS Journal of Surfaces and Colloids

|March 29, 2011

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We developed a novel thermoresponsive microgel SERS substrate with magnetic and silver particles. It efficiently captures and concentrates analytes, enhancing detection limits for environmental pollutants like pentachlorophenol.

Area of Science:

Materials Science
Nanotechnology
Analytical Chemistry

Background:

Surface-Enhanced Raman Spectroscopy (SERS) requires efficient substrates for sensitive analyte detection.
Thermoresponsive polymers offer tunable properties for controlled analyte interaction.
Magnetic nanoparticles enable sample preconcentration and manipulation.

Purpose of the Study:

To fabricate a novel SERS substrate using magnetic and silver nanoparticles within a thermoresponsive poly(N-isopropylacrylamide) (pNIPAM) microgel.
To demonstrate the substrate's ability to adsorb analytes at low temperatures and generate hot spots upon heating or drying.
To showcase the magnetic functionality for analyte concentration and improved SERS detection limits.

Main Methods:

Fabrication of pNIPAM microgels encapsulating magnetic and silver nanoparticles.

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Optical Trapping of Nanoparticles

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Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

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Published on: November 17, 2023

Utilizing temperature changes to control microgel swelling/collapse for analyte adsorption and hot spot generation.

Employing magnetic fields for concentrating the SERS substrate and adsorbed analytes.

Performing SERS analysis on pentachlorophenol (PCP) as a model environmental pollutant.

Main Results:

Successful synthesis of magnetic/silver nanoparticle-loaded pNIPAM microgel SERS substrates.
Demonstrated reversible adsorption of analytes with temperature changes.
Achieved enhanced SERS detection limits due to analyte preconcentration via magnetic fields.
First-time SERS analysis of pentachlorophenol (PCP) using this novel substrate.

Conclusions:

The developed thermoresponsive magnetic microgel SERS substrate offers a promising platform for sensitive and efficient analyte detection.
The combination of thermoresponsiveness and magnetic guidance allows for controlled analyte sequestration and signal amplification.
This technology has significant potential for environmental monitoring and analysis of trace pollutants.