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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

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Published on: June 30, 2014

Cognitive functioning in multiple sclerosis.

Laura J Julian1

  • 1Department of Medicine, University of California San Francisco, 3333 California Street, STE 270, San Francisco, CA 94143-0920, USA. laura.julian@ucsf.edu

Neurologic Clinics
|March 29, 2011
PubMed
Summary
This summary is machine-generated.

Cognitive dysfunction in multiple sclerosis (MS) is reviewed, covering its nature, risk factors, and assessment. This summary also includes pediatric MS cognition and potential interventions for cognitive problems.

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Area of Science:

  • Neurology
  • Neuroscience
  • Cognitive Science

Background:

  • Multiple sclerosis (MS) is characterized by diffuse neuropathology impacting cognitive functions.
  • Cognitive impairment is a significant aspect of MS, affecting various domains.
  • Understanding risk and protective factors is crucial for managing MS-related cognitive dysfunction.

Purpose of the Study:

  • To review the nature and course of cognitive dysfunction in MS.
  • To discuss factors influencing the development of cognitive impairment in MS.
  • To explore assessment, screening, and intervention strategies for cognitive problems in MS, including pediatric cases.

Main Methods:

  • Literature review of recent advances in MS neuropathology and cognitive function.
  • Synthesis of information on risk and protective factors for cognitive impairment.
  • Discussion of assessment tools and screening approaches for MS-related cognitive dysfunction.
  • Inclusion of pediatric-onset MS cognition and intervention strategies.

Main Results:

  • Cognitive dysfunction in MS is linked to diffuse neuropathology.
  • Specific factors can increase or decrease the risk of cognitive impairment.
  • Various assessment and screening methods are available for MS-related cognitive issues.
  • Intervention strategies show promise for treating cognitive problems in MS.

Conclusions:

  • Cognitive dysfunction is a complex manifestation of MS, influenced by neuropathology and individual factors.
  • Comprehensive assessment and targeted interventions are essential for managing cognitive impairment in MS patients.
  • Addressing cognitive issues in both adult and pediatric MS populations is critical for improving quality of life.