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Updated: Jun 3, 2026
06:23
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
Coagulation biomarkers in critically ill patients.
Marcel Levi1, Marcus Schultz, Tom van der Poll
1Department of Vascular Medicine and Internal Medicine, Academic Medical Centre F-4, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. m.m.levi@amc.uva.nl
Critical Care Clinics
|March 29, 2011
Summary
Critically ill patients often experience coagulation abnormalities impacting outcomes. Understanding causes guides specific treatments like transfusions or prohemostatic therapies for better patient management.
Area of Science:
- Critical care medicine
- Hematology
- Pathophysiology
Background:
- Coagulation abnormalities are frequent in critically ill patients.
- These abnormalities significantly impact patient outcomes.
- Identifying underlying causes is crucial for effective treatment.
Purpose of the Study:
- To discuss the role of coagulation biomarkers in critically ill patients.
- To highlight the importance of understanding the causes of coagulation disorders.
- To review therapeutic strategies for managing bleeding and thrombosis.
Main Methods:
- Review of current literature on coagulation biomarkers.
- Discussion of diagnostic approaches for coagulation abnormalities.
- Analysis of treatment options including transfusions and specific therapies.
Main Results:
- Coagulation disorders necessitate tailored treatment based on underlying causes.
- Platelet concentrate and plasma products address deficiencies in bleeding patients.
- Prohemostatic treatment and restoration of anticoagulant pathways offer targeted interventions.
Conclusions:
- Accurate diagnosis of coagulation issues in critical illness is vital.
- Therapeutic strategies should be individualized to patient needs.
- Management of coagulation biomarkers guides supportive and specific treatments for improved prognosis.
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