Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: The Texas Community-Engagement Research Alliance Against COVID-19 in Disproportionately Affected Communities (TX CEAL) Consortium - CORRIGENDUM.

Journal of clinical and translational science·2025
Same author

Economic impact of managing invasive mold disease with isavuconazole compared with liposomal amphotericin B followed by posaconazole in Spain.

Expert review of anti-infective therapy·2024
Same author

Risk of Multidrug-Resistant Pathogens in Severe Community-Acquired Pneumonia.

Seminars in respiratory and critical care medicine·2024
Same author

Risk factors associated with mortality among elderly patients with COVID-19: Data from 55 intensive care units in Spain.

Pulmonology·2023
Same author

Time to decision in sepsis.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022
Same author

Current treatment of nosocomial pneumonia and ventilator-associated pneumonia.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022

Related Experiment Video

Updated: Jun 3, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

Effectiveness of treatments for severe sepsis: data from the bundle implementation programs.

R Ferrer1, A Artigas

  • 1Critical Care Center, Hospital de Sabadell, CIBER Enfermedades Respiratorias, Instituto Universitario Parc Tauli, Universidad Autónoma de Barcelona, Spain. rferrer@tauli.cat

Minerva Anestesiologica
|March 29, 2011
PubMed
Summary

Bundled care improves survival in severe sepsis. Early recognition and treatments like broad-spectrum antibiotics and activated protein C are key components for better sepsis outcomes.

More Related Videos

Cecal Ligation Puncture Procedure
11:53

Cecal Ligation Puncture Procedure

Published on: May 7, 2011

Related Experiment Videos

Last Updated: Jun 3, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

Cecal Ligation Puncture Procedure
11:53

Cecal Ligation Puncture Procedure

Published on: May 7, 2011

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Health Services Research

Background:

  • Severe sepsis management has evolved with quality improvement initiatives.
  • Bundled care strategies have demonstrated potential to enhance patient survival rates.
  • Analyzing the effectiveness of specific treatments within sepsis bundles is crucial.

Purpose of the Study:

  • To analyze the effectiveness of treatments included in bundled care for severe sepsis.
  • To evaluate the impact of specific interventions on sepsis outcomes.
  • To provide evidence supporting the implementation of comprehensive sepsis bundles.

Main Methods:

  • Analysis of observational studies on severe sepsis treatments.
  • Utilized propensity scores and statistical adjustments to minimize bias.
  • Focused on treatments such as early antibiotics, activated protein C, and mechanical ventilation support.

Main Results:

  • Early sepsis recognition and broad-spectrum antibiotics significantly improve outcomes.
  • Specific treatments for shock (e.g., activated protein C) are effective.
  • Mechanical ventilation management within bundles also contributes to better survival.

Conclusions:

  • Bundled care is a proven strategy for improving severe sepsis survival.
  • Hospitals should adopt evidence-based bundled care protocols.
  • Early recognition and targeted interventions are critical for effective severe sepsis management.