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Updated: Jun 3, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
Published on: May 19, 2015
Depression and attention to two kinds of meaning: A cognitive perspective
1MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 7EF, UK.
Abstract:
The complexity of a mental disorder such as depression is such that a way of interlinking the neural, mental and interpersonal levels is needed. This paper proposes that a theoretical framework which distinguishes, and relates, macro-theory and micro-theory at these levels can serve this purpose. The 'Interacting Cognitive Subsystems' approach to mental architecture is used to show how, via the detailed specification of mental processes and representations, a macro-theory of mental architecture contributes to our understanding of depressed states. In the account advanced by Teasdale and Barnard depressed states are seen as being maintained by an abnormal version of a dynamic dialogue between two qualitatively distinct types of meaning: one is referentially specific, propositional meaning, the other consists of holistic schemata rich in latent content and is called implicational meaning. In depressed states with ruminative and avoidant thought patterns, the mental function of attention is seen as being directed preferentially at propositional meanings. There is a corresponding neglect of attention to implicational meanings. The paper concludes with a brief discussion of how this approach can address transdiagnostic issues and how it may suggest new strategies for therapeutic interventions.
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