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Updated: Jun 3, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells

Published on: December 27, 2017

Thrombocytopenia in pregnancy.

Paula L Bockenstedt¹

¹Division of Hematology/Oncology, University of Michigan Medical Center, University of Michigan, Ann Arbor, MI 48105, USA. pbockens@umich.edu

Hematology/Oncology Clinics of North America

|March 30, 2011

Summary

Most pregnancy thrombocytopenia is benign. However, 35% indicate serious conditions requiring hematological and obstetric consultation for maternal and fetal well-being.

Area of Science:

Obstetrics
Hematology
Perinatology

Background:

Thrombocytopenia, or low platelet count, is common in pregnancy.
While often benign, it can signal serious underlying conditions.

Purpose of the Study:

To highlight the importance of evaluating thrombocytopenia in pregnancy.
To differentiate benign cases from those requiring intervention.

Main Methods:

Review of clinical cases and literature.
Hematological assessment of pregnant patients with low platelet counts.

Main Results:

Approximately 35% of thrombocytopenia cases in pregnancy are linked to significant disease.
These cases may present risks of serious bleeding during delivery.

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Last Updated: Jun 3, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells

Published on: December 27, 2017

Low platelet counts can indicate severe systemic disorders needing urgent care.

Conclusions:

All pregnant women with platelet counts below 100,000/μL need expert consultation.
Hematological and obstetric evaluation is crucial to rule out severe conditions.
Prompt diagnosis ensures appropriate maternal and fetal care.